Expanding our knowledge and helping the community
Participants over the past 6 years
Actively Enrolling studies
Clinical trials investigate the use of an intervention such as a drug or medical device in people. These trials help determine if a treatment or prevention is safe and effective for people to use, or they can monitor the long-term use of an intervention.
ROC Foundation's Focus
OR3o Total Hip Arthroplasty
Oxinium DH Total Hip Arthroplasty
R3 Total Hip Arthroplasty
Retrospective JIIXR Total Knee Arthroplasty
Wellframe Mobile App Validation
Wellframe Mobile App Feasibility
J2 Flouro Study
JIIXR Total Knee Arthroplasty
LEGION Total Knee Arthroplasty
Retrospective JIICR Total Knee Arthroplasty
The ROC Foundation supports orthopedic clinical trials overseen by our orthopedic surgeons. We help conduct Phase 3 and 4 trials which can be sponsor or physician initiated. We are currently involved with a diabetic foot study, a trauma study, and several joint replacement studies.
Looking For More?
If you have further questions regarding research, please contact email@example.com.
What is the difference between a Phase 3 and 4 trial?In phase 3 trials, an experimental study drug or device is used in a large group of people. Researchers then compare it to commonly used treatments, determine its effectiveness and monitor for side effects. This information will allow the drug or device to be used safely and gain full approval from the FDA, making it available to patients outside of a clinical study. Phase 4 trials, also called post-marketing studies, are conducted after a treatment is approved for use by the FDA. They can provide additional information including the intervention’s risks, benefits, best use practices, and effects from long-term use.
What is a sponsor initiated study?A sponsor can be an individual, pharmaceutical company, governmental agency, academic institution, private organization, or other organization and can initiate a study. The ROC Foundation primarily partners with medical device companies who are required to do post-market surveillance studies on their devices. Sponsors oversee the study to make sure it is compliant with regulations and review the de-identified data. They are not involved in the day-to-day research activities and data collection, which is run by the primary investigator (a ROC surgeon) and research staff (ROC Foundation staff).
What is a physician-initiated study?Physician-initiated studies are studies started and run by physicians without the involvement of a sponsor. These studies still must follow regulations and gain approval through the local authority just as the sponsor-initiated studies do.
Why do people participate in clinical trials?People may participate in studies with the goals of advancing medical knowledge and helping others. They may also participate to have access to a newer treatment.
How do I participate in a clinical trial?For current active studies that are recruiting participants, if your designated physician who is also involved in research deems you a good candidate for a study (i.e., all eligibility criteria is met), the research staff will introduce and discuss the study with you. If you do decide to participate, you will sign an informed consent form. You will be officially participating in the study once the consent form has all the appropriate signatures.
What are the benefits of participating in a clinical trial?Participating in clinical research greatly contributes to knowledge and improvement of medical technology and interventions. It cannot be guaranteed that the participant will receive any medical benefits from being in the study.
How Do You Safeguard My Privacy?The ROC Foundation follows HIPAA regulations. Only authorized personnel (e.g., research staff, etc.) may access the patient’s records for only the purpose of their job.
Why are total hip/knee replacements performed?Total joint replacements are performed in patients suffering from severe joint pain and instability due to conditions like arthritis.